Mac formed his fist band, The Dominos, in the late 1950’s and by 1956 he was playing in record sessions backing and learning from many of the New Orleans legends such as Professor Longhair, Dave Bartholomew, Paul Gayten, Frankie Ford, James Booker and Earl King. During the mid 1960’s Rebennack moved to Los Angeles, where he worked on sessions with Sonny & Cher, Eric Clapton, Mick Jagger, The O-Jays and numerous others. He began his solo recording career in 1968 as Dr. John and received his largest commercial success in 1973 with the release of "In The Right Place" produced by Allen Toussaint and featuring two hit singles, "Right Place, Wrong Time" and "Such A Night."
Dr. John’s rasping, haunted voice is easily recognized as he plays a music that draws upon the rich musical heritage of New Orleans --a music he calls "the fonk." Music that combines R&B, jazz, gut-bucket blues, gospel, spirituals, Latin, Dixieland and pop. After more than four decades of playing New Orleans music and living in the fast lane, Mac Rebennack remains a survivor. His stage show serves up a diverse musical gumbo of New Orleans music including street marches, blues, R&B, Dixieland, southern funk and rock ‘n’ roll, with some of the best boogie-woogie piano playing found anywhere. Dr. John’s newest release "Television," features more of the same exuberant piano playing, infectious good-time grooves and gravely wit that has made Dr. John a true New Orleans icon.